The Damage


Tylenol® can be very rough on the liver. In fact, Tylenol® and Acetaminophen, the generic form of the medicine,  are the most common cause of acute (sudden) liver failure in the United States; they are believed to cause 3 times as many cases of liver failure as all other drugs combined. Once the liver fails, the only treatment that can prevent death is a liver transplant. A person with a liver transplant will experience a lifetime of medical care and result in hundreds of thousands of dollars in medical expenses. McNeil-PPC, Inc., the maker of Tylenol® has known for years of the dangers of Tylenol® but has not share their information with doctors or consumers.


The liver’s main job is to filter the blood coming from the digestive tract, before passing it to the rest of the body. The liver also detoxifies chemicals and metabolizes drugs. After a person has taken Tylenol®  the medication enters the blood through the digestive tract and the blood carries it to the liver where it is metabolized (broken down) into other non-toxic (not harmful) substances. During this metabolic process, known as glucuronidation, a small amount of a toxic substance known as N-acetyl-p-benzoquinone imine (NAPQI) is produced. The small amount of NAPQI is normally not a problem in the liver because it is further broken down into non-toxic substances by Glutathione. However, the liver cannot metabolize a large dose of Acetaminophen. The liver is overwhelmed with too much Acetaminophen because all of the Glutathione is quickly used up, which means the liver is left with a large amount of NAPQI to deal with. When NAPQI accumulates in the liver, it destroys liver cells and causes significant liver damage, and even liver failure. People who regularly drink alcohol can deplete the liver’s supply of Glutathione quickly so that the liver does not have enough Glutathione to break down even small amounts of Acetaminophen. There is also some scientific evidence showing that those who drink a lot of soft drinks and coffee containing caffeine can triple the amount of NAPQI in their blood, also destroying liver cells.

People who have the highest risk for Tylenol® related liver failure include: heavy drinkers (those who drink more than 3 alcoholic drinks per day), elderly men, people who are thin, people who are fasting, people with poor diets, heavy caffeine drinkers and people with preexisting liver or kidney damage.

A study published in the journal of the American Medical Association in 2006, reported that healthy adults who took the maximum recommended dose of Tylenol® for just two weeks showed abnormal liver tests results. The liver damage usually shows up on liver function blood tests. If the liver enzymes are elevated, this is evidence of liver damage. If someone suffers enough damage to their liver, they will end up with liver failure. If the person does not receive a liver transplant, the person will die. Even with a liver transplant, a person’s life will never be the same. There will be many medical issues to deal with. There will also be a lifetime of medical care and hundreds of thousands in medical expenses.

Dr. Gerald Dal Pan, Director of the FDA’s Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, said that has many as 800 cases of liver failure each year may be linked to the overuse of Tylenol®. Also, the American Liver Damage Caused by Tlenol or AcetaminophenAssociation for the Study of Liver Diseases estimates that over 500 people die each year from the accidental or unintentional overdose of Tylenol® or Acetaminophen. We believe these are actually low because over 25,000 people a year are believed to be admitted into the hospital each year for liver problems associated with Tylenol related liver damage.

Our team of experienced lawyers and legal professionals have already successfully helped of clients and families recover for injuries, and deaths, caused by the unintentional or accidental overdose of Tylenol® . We are representing people seeking compensation from McNiel,  the makers of Tylenol due to serious injuries like failure or death. We have the experience you are looking for and are ready to help you today! If you, or a loved one, believe you have suffered serious medical injuries, such as liver damage, liver failure, kidney damage, or even death, after taking Tylenol® , or other medications containing this drug, please call our experienced lawyers now at 1-800-321-4477 for a free, confidential case evaluation. You may be entitled to an award of significant compensation. We can help you recover for past medical bills, future medical bills, future medical care, pain and suffering and other harms and losses.

There are certain time restrictions on when you must file your claim and missing these time deadlines can mean you have lost the right to recover even if you have a valid claim. Therefore, call us at 1-800-321-4477 to start an evaluation now! If we do not help you obtain a recovery, you owe us nothing!

Free Case Evaluation Submission
Please contact us for your FREE case evaluation today. We will be in contact with you shortly.